JMagnResonImaging.Apr;43(4):-.doi:10./jmri..
3.0T磁共振下乳腺肿块的良恶性鉴别：基于整个病灶ADC的柱状图分析
Characterizationofbreastmassesasbenignormalignantat3.0TMRIwithwhole-lesionhistogramanalysisoftheapparentdiffusioncoefficient
SuoS1,ZhangK1,CaoM1,SuoX2,HuaJ1,GengX1,ChenJ1,ZhuangZ1,JiX3,LuQ1,WangH4,XuJ1.
1DepartmentofRadiology,RenJiHospital,SchoolofMedicine,ShanghaiJiaoTongUniversity,Shanghai,China.
2SchoolofMedicalImaging,TianjinMedicalUniversity,Tianjin,China.
3SchoolofBiomedicalEngineering,ShanghaiJiaoTongUniversity,Shanghai,China.
4PhilipsResearchChina,Shanghai,China.
PURPOSE:
Toinvestigatetheutilityofwhole-lesionapparentdiffusioncoefficient(ADC)histogramanalysisincapturingbreastlesionheterogeneityanddeterminewhichADCmetricmayhelpbestdifferentiatebenignfrommalignantbreastmasslesionsat3.0Tmagneticresonanceimaging(MRI).
MATERIALSANDMETHODS:
Weretrospectivelyincludedwomenwithbreastmasslesions(benign:malignant?=?36:65)whounderwent3.0Tdiffusion-weightedimaging(DWI)andsubsequentlyhadhistopathologicconfirmation.ADChistogramparameters,includingthemean,minimum,maximum,10th/25th/50th/75th/90thpercentile,skewness,kurtosis,andentropyADCs,werederivedforthewhole-lesionvolumeineachpatient.Mann-WhitneyU-test,univariateandmultivariatelogisticregression,areaunderthereceiver-operatingcharacteristiccurve(Az),intraclasscorrelationcoefficient(ICC),andBland-Altmantestwereusedforstatisticalanalysis.
RESULTS:
Mean,minimum,maximum,and10th/25th/50th/75th/90thpercentileADCsweresignificantlylower(allP0.),whileskewnessandentropyADCsweresignificantlyhigher(P0.andP?=?0.,respectively)inmalignantlesions公益爱心援助定点医院北京中科中医院好不好
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